Program
Wednesday, June 1, 2022
Arrival
Reception at the Nobel Forum 18:00-21:00. Light refreshments and drinks will be provided.
Thursday, June 2, 2022
Registration at the Nobel Forum 08:00 -17:00
09:00 – 9:10 Welcome and introduction (Åke Lernmark and Olle Kämpe)
Session 1: Infant development of immune and autoimmune responses
Chairs: Beena Akolkar NIDDK, NIH & Helena Elding Larsson, Malmö, Sweden
09:10 – 09:15 Beena Akolkar, NIDDK, MD, USA – Introduction (rapporteur)
09:15 – 09:45 Infant development of the immune response.
Petter Brodin, Stockholm, Sweden
09:45 – 10:15 Age dependent immunity and autoimmunity.
Eoin McKinney, Cambridge, UK
10:15 – 10:40 Dendritic cell development before two years of age.
Ezio Bonifacio, Dresden, Germany
10:40 – 11:00 Discussion
11.00 – 11.15 Coffee
Session 2: Immune tolerance
Chairs: Åke Lernmark, Malmö, Sweden & Jorma Toppari, Turku, Finland
11.15 – 11:20 Jorma Toppari, Turku, Finland - Introduction (rapporteur)
11.20 – 11:50 Thymic role in infant tolerance induction.
Mark Anderson, San Francisco, CA, USA
11.50 – 12:20 Immune tolerance, superantigen responses and multisystem inflammatory syndrome in SARS – CoV2 infection.
Moshe Arditi, Cedars-Sinai Medical Center, Los Angeles, CA,USA
12:20 – 12:35 Discussion
12:30 – 13:15 Lunch
Session 3: Herd immunity, mother – child immune response development and infant immune responses to virus infections and vaccination
Chairs: Marian Rewers, Denver, USA & Olle Kämpe, Stockholm, Sweden
13:15 – 13:20 Marian Rewers, Denver, CO, USA – Introduction (rapporteur)
13:20 – 13:50 Heard immunity and infant immune responses to virus infections.
Heikki Hyöty, Tampere, Finland
13:50 – 14:20 Genetic and environmental factors driving inter-individual immune response variation.
Lluis Quintana-Murci, Paris, France
14:20 – 14.45 Coffee
14:45 – 15:15 Systems vaccinology in infants.
Bali Pulendran, Stanford, CA, USA
15:15 – 15:45 Infant viral infections and control by vaccine responses.
Galit Alter, Cambridge, MA, USA
15:45 – 16:15 The Healthy Baby Initiative: Prevention of Childhood Disease by Targeting Microbiomes, Epithelial Barriers, and Immune Development. Richard Insel, Janssen R&D, USA
16:15 – 16:45 Discussion
16:45 – 18:00 Poster session & discussions
19:00 Symposium dinner
Friday, June 3, 2022
Session 4: Staging the human microbiome and virome development
Chairs: Anette Ziegler, Munich, Germany & Petter Brodin, Stockholm, Sweden
08:30 – 08:35 Anette Ziegler, Munich, Germany – Introduction (rapporteur)
08:35 – 09:05 Childhood microbiome and immunity.
Joseph Petrosino; Houston, TX, USA
09:05 - 09:35 Infant microbiome and the developing immune response.
Ramnik Xavier, Cambridge, MA, USA
09:35 – 10:05 TBD
Jayne Danska, Toronto, Canada
10:05 – 10:35 Staging the infant virome.
Richard Lloyd, Houston, TX, USA
10:35 – 10:50 Discussion
10:50 – 11:05 Coffee
Session 5: Infant growth, metabolomics, immunity and autoimmunity
Chairs: Outi Mäkitie, Stockholm, Sweden & Carin Andrén Aronsson, Malmö, Sweden
11:05 – 11.10 Outi Mäkitie, Stockholm, Sweden – Introduction (rapporteur)
11:10 – 11:40 Infant metabolomics and islet autoimmunity risk.
Kendra Vehik, Tampa, FL, USA
11:40 – 12:10 Growth and autoimmunity molecular defects.
Cheri Deal, Montreal, Canada
12:10 – 12.40 Food intake, gluten immunity and celiac disease autoimmunity
Ludvig Sollid, Oslo, Norway
12:40 – 13:00 Discussion
13:00 – 14:00 Lunch
Session 6: The autoantigenome and cell-specific autoimmunity
Chairs: Richard McIndoe, Augusta, USA & Daniel Agardh, Malmö, Sweden
14:00 – 14:05 Richard McIndoe, Augusta, GE, USA – Introduction (rapporteur)
14:05 – 14:35 The infant autoantigenome.
Olle Kämpe, Stockholm, Sweden
14:35 – 15:05 First appearing autoantibodies – prospects for different etiologies in autoimmune diabetes.
Jeffrey Krischer, Tampa, FL, USA
15:05 – 15:35 Infant TCR and celiac disease specific T-cells.
Mark Davis, Stanford, CA, USA
15:35 – 15:50 Discussion
15:50 – 16:00 Coffee
Session 7: Inborn errors and infections
Chairs: William Hagopian, Seattle, USA & Anna Wedell, Stockholm, Sweden
16:00 – 16:05 William Hagopian, Seattle, WA, USA – Introduction (rapporteur)
16:05 – 16:35 Tissue-specific mechanisms of antifungal immunity: Lessons from inborn errors or immunity.
Michail S Lionakis, Bethesda, MA, USA
16:35 – 17:05 Primary immunodeficiency and B cell malignancy
Qiang Pan Hammarström, Stockholm, Sweden
17:05 – 17:35 Different inborn errors of immunity underlie childhood COVID-19 pneumonia and MIS-C
Jean-Laurent Casanova, New York, NY, USA
17:35 – 17:50 Discussion
17:50 – 18:00 Concluding remarks
Åke Lernmark and Olle Kämpe
18:00 After Work & mingle
