1 Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden
2 Theme Inflammation and Aging, Karolinska University Hospital, Stockholm, Sweden
3 Department of Geriatric medicine, Jakobsbergsgeriatriken, Stockholm, Sweden
4 Department of Geriatric medicine, Sabbatsbergsgeriatriken, Stockholm, Sweden
5 Department of Geriatric medicine, Dalengeriatriken Aleris Närsjukvård AB, Stockholm, Sweden
6 Department of Geriatric medicine, Capio geriatrik Löwet, Stockholm, Sweden
7 Department of Geriatric medicine, Capio geriatrik Sollentuna, Stockholm, Sweden
8 Department of Geriatric medicine, Capio Geriatrik Nacka AB, Nacka, Sweden
9 Department of Geriatric medicine, Handengeriatriken, Aleris Närsjukvård AB, Stockholm, Sweden
10 Division of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden
11 R&D unit, Stockholms Sjukhem, Stockholm, Sweden
Bakgrund: To describe the changes over time in 30-day mortality of geriatric patients in the Stochholm GeroCovid cohort, and incidence and mortality from COVID-19 in a population over 70 in the Stockholm region, March 2020-July 2021.
Metod: 4,565 patients over 70 years old with COVID-19 and 19,308 hospitalized for non-COVID-19 causes from March 6, 2020, to July 31, 2021, were included. Across the date of hospital admission, patient demographics, treatment, care, and mortality were collected.
Resultat: In patients with COVID-19, the 30-day mortality was highest at the beginning of the first wave (29% in March-April 2020), decreased as the first wave subsided (6% July-August), increased again in the second wave (18% September-December, and 14% January-February), but failed to increase as much in the third wave (11-14% March-July 2021). In non-COVID-19 geriatric patients, 30-day mortality presented a similar trend, but with a smaller magnitude of variation (4-9%). The number of persons over 70 years testing positive for COVID-19 in Stockholm reached two peaks in 2020 (April and December), then fell in January 2021, and then increased again. We observe a similar trend in the number of COVID-19-related deaths in persons over 70 years old in Stockholm except for the third wave (probably vaccine effect).
Slutsats: During the first and second waves, 30-day mortality for hospitalized geriatric COVID-19 patients increased in periods of high community COVID-19 incidence and hospital admissions. Mortality for non-COVID geriatric cases varied less but also increased with the pandemic peaks.