P35 – Mortality of patients admitted to geriatric care from March 2020 to July 2021: Data from the Stockholm Gero-COVID cohort

3. Epidemiologi

Hong Xu1, Sara Garcia-Ptacek1, 2, Martin Annetorp2, Viktoria Bäck Jerlardtz3, Tommy Cederholm2, Malin Engström4, Miia Kivipelto1, 2, Lars Göran Lundberg5, Carina Metzner2, Maria Olsson6, 7, Josefina Skogö Nyvang8, Carina Sühl Öberg9, Elisabet Åkesson10, 11, Dorota Religa Dorota Religa1, 2, Maria Eriksdotter1, 2

1 Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden
2 Theme Inflammation and Aging, Karolinska University Hospital, Stockholm, Sweden
3 Department of Geriatric medicine, Jakobsbergsgeriatriken, Stockholm, Sweden
4 Department of Geriatric medicine, Sabbatsbergsgeriatriken, Stockholm, Sweden
5 Department of Geriatric medicine, Dalengeriatriken Aleris Närsjukvård AB, Stockholm, Sweden
6 Department of Geriatric medicine, Capio geriatrik Löwet, Stockholm, Sweden
7 Department of Geriatric medicine, Capio geriatrik Sollentuna, Stockholm, Sweden
8 Department of Geriatric medicine, Capio Geriatrik Nacka AB, Nacka, Sweden
9 Department of Geriatric medicine, Handengeriatriken, Aleris Närsjukvård AB, Stockholm, Sweden
10 Division of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden
11 R&D unit, Stockholms Sjukhem, Stockholm, Sweden

Bakgrund: To describe the changes over time in 30-day mortality of geriatric patients in the Stochholm GeroCovid cohort, and incidence and mortality from COVID-19 in a population over 70 in the Stockholm region, March 2020-July 2021.

Metod: 4,565 patients over 70 years old with COVID-19 and 19,308 hospitalized for non-COVID-19 causes from March 6, 2020, to July 31, 2021, were included. Across the date of hospital admission, patient demographics, treatment, care, and mortality were collected.

Resultat: In patients with COVID-19, the 30-day mortality was highest at the beginning of the first wave (29% in March-April 2020), decreased as the first wave subsided (6% July-August), increased again in the second wave (18% September-December, and 14% January-February), but failed to increase as much in the third wave (11-14% March-July 2021). In non-COVID-19 geriatric patients, 30-day mortality presented a similar trend, but with a smaller magnitude of variation (4-9%). The number of persons over 70 years testing positive for COVID-19 in Stockholm reached two peaks in 2020 (April and December), then fell in January 2021, and then increased again. We observe a similar trend in the number of COVID-19-related deaths in persons over 70 years old in Stockholm except for the third wave (probably vaccine effect). 

Slutsats: During the first and second waves, 30-day mortality for hospitalized geriatric COVID-19 patients increased in periods of high community COVID-19 incidence and hospital admissions. Mortality for non-COVID geriatric cases varied less but also increased with the pandemic peaks.